BONE MATRIX
Bone matrix is the intercellular substance of bone tissue
consisting of collagen fibers, ground substance, and inorganic bonesalts. This matrix
is secreted by the cells. It consists of protein fibers.
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Bone is
composed of both organic and inorganic components. Inorganiccomponents
include calcium hydroxyapatite and osteoclasia phosphate. Organic components include collagen, proteoglycans, matrix
proteins, cytokines and growth factors.
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Bone is
a dynamic tissue that is constantly being reshaped by osteoblasts,
whichproduce and secrete matrix proteins and transport mineral
into the matrix, and osteoclasts, which break down the tissues.
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Both bone and
cartilage contain living cells embedded in an
intercellular matrix. Inbone, these cells are called osteocytes, which
likewise occupy lacunae. However, the
intercellular matrix of bone contains more collagen than
found in cartilage and it is heavily mineralized with calcium salts.
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